Article
Increased mitochondrial oxidative phosphorylation in the liver is associated with obesity and insulin resistance.
Obesity (Silver Spring, Md.) - 1 May 2011
Buchner David A, Yazbek Soha N, Solinas Paola, Burrage Lindsay C, Morgan Michael G, Hoppel Charles L, Nadeau Joseph H
Abstract excerpt
Obesity is the result of excess energy intake relative to expenditure, however little is known about why some individuals are more prone to weight gain than others. Inbred strains of mice also vary in their susceptibility to obesity and therefore represent a valuable model to study the genetics and physiology of weight gain and its co-morbidities such as type 2 diabetes. C57BL/6J mice are susceptible to obesity...
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