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Article

Variation in type 2 diabetes--related traits in mouse strains susceptible to diet-induced obesity.

Diabetes - 1 Aug 2003

Rossmeisl Martin, Rim Jong S, Koza Robert A, Kozak Leslie P

Abstract excerpt

C57BL/6J (B6) and AKR/J (AKR) inbred strains of mice develop a comparable degree of obesity when fed a high-fat diet. However, although obese B6 mice are more glucose intolerant, obese AKR mice are more insulin resistant. To understand the basis for these strain differences, we characterized features of adiposity and glucose homeostasis in mice fed a high-fat diet for 8 weeks. The results indicated that despite...

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Identifiers

PMID: 12882911
DOI: 10.2337/diabetes.52.8.1958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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