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Article

Phenotypic divergence in two lines of L-Fabp-/- mice reflects substrain differences and environmental modifiers.

American journal of physiology. Gastrointestinal and liver physiology - 15 Oct 2015

Newberry Elizabeth P, Kennedy Susan, Xie Yan, Luo Jianyang, Jiang Hui, Ory Daniel S, Davidson Nicholas O

Abstract excerpt

Phenotypic divergence in diet-induced obesity (DIO) and hepatic steatosis has been reported in two independently generated lines of L-Fabp(-/-) mice [New Jersey (NJ) L-Fabp(-/-) vs. Washington University (WU) L-Fabp(-/-) mice]. We performed side-by-side studies to examine differences between the lines and investigate the role of genetic background, intestinal microbiota, sex, and diet in the divergent phenotypes....

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Identifiers

PMID: 26251469
DOI: 10.1152/ajpgi.00170.2015
PMCID: PMC4609928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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