Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis.

Oncogene - 28 Nov 2002

Brachat Arndt, Pierrat Benoit, Xynos Alexandros, Brecht Karin, Simonen Marjo, Brüngger Adrian, Heim Jutta

Abstract excerpt

DNA microarrays are powerful tools for the analysis of gene expression on a genomic scale. The importance of individual regulatory events for the process under study can however not be deduced unequivocally without additional experiments. We devised a strategy to identify central regulators of ca...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Apoptosis
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Expressed Sequence Tags

Share to Flow Cytometry

Share to Interleukin-3

Share to Oligonucleotide Array Sequence Analysis

Share to Staurosporine

Source

Identifiers

PMID: 12447701
DOI: 10.1038/sj.onc.1206016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12447701-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis.PMID 12447701Read ↗

Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomasSemantic proximity Read ↗

The resistance of B-CLL cells to DNA damage-induced apoptosis defined by DNA microarraysSemantic proximity Read ↗

Strong Activation of p53 by Actinomycin D and Nutlin-3a Overcomes Resistance of Cancer Cells to the Pro-apoptotic Activity of FAS LigandSemantic proximity Read ↗

Microarray Analysis Uncovers the Induction of the Proapoptotic BH3-only Protein Bim in Multiple Models of Glucocorticoid-induced ApoptosisSemantic proximity Read ↗

A chemical genetics approach for the discovery of apoptosis inducers: from phenotypic cell based HTS assay and structure-activity relationship studies, to identification of potential anticancer agents and molecular targets.Semantic proximity Read ↗

Gene expression of anti‐ and pro‐apoptotic proteins in malignant and normal plasma cellsSemantic proximity Read ↗

Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcriptsSemantic proximity Read ↗

A high-throughput screen for single gene activities: isolation of apoptosis inducers.Semantic proximity Read ↗

A global approach combining proteome analysis and phenotypic screening with RNA interference yields novel apoptosis regulators.Semantic proximity Read ↗

A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion.Semantic proximity Read ↗

Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.Semantic proximity Read ↗

Isolation of p53‐target genes and their functional analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.