Article
A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis.
Oncogene - 28 Nov 2002
Brachat Arndt, Pierrat Benoit, Xynos Alexandros, Brecht Karin, Simonen Marjo, Brüngger Adrian, Heim Jutta
Abstract excerpt
DNA microarrays are powerful tools for the analysis of gene expression on a genomic scale. The importance of individual regulatory events for the process under study can however not be deduced unequivocally without additional experiments. We devised a strategy to identify central regulators of cancer drug responses by combining the results of microarray experiments with efficient methods for phenotypic testing of...
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