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Article

A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion.

Cancer research - 15 Mar 2009

Santos Javier, González-Sánchez Laura, Matabuena-Deyzaguirre María, Villa-Morales María, Cozar Patricia, López-Nieva Pilar, Fernández-Navarro Pablo, Fresno Manuel, Díaz-Muñoz Manuel D, Guenet Jean-Louis, Montagutelli Xavier, Fernández-Piqueras José

Abstract excerpt

Cancer susceptibility is essentially attributable to multiple low-penetrance genes. Using interspecific consomic and congenic mice between the tumor-resistant SEG/Pas and the tumor-sensitive C57BL/6J strains, a region on chromosome 19 involved in the genetic resistance to gamma-irradiation-induced T-cell lymphomas (Tlyr1) has been identified. Through the development of nonoverlapping subcongenic strains, it has...

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Identifiers

PMID: 19244132
DOI: 10.1158/0008-5472.CAN-08-1821

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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