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Article

Transcription-dependent increase in multiple classes of base substitution mutations in Escherichia coli.

Journal of bacteriology - 1 Dec 2002

Klapacz Joanna, Bhagwat Ashok S

Abstract excerpt

We showed previously that transcription in Escherichia coli promotes C. G-to-T. A transitions due to increased deamination of cytosines to uracils in the nontranscribed but not the transcribed strand (A. Beletskii and A. S. Bhagwat, Proc. Natl. Acad. Sci. USA 93:13919-13924, 1996). To study mutations other than that of C to T, we developed a new genetic assay that selects only base substitution mutations and...

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Identifiers

PMID: 12446637
DOI: 10.1128/JB.184.24.6866-6872.2002
PMCID: PMC135453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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