Article
Association of ulcerative colitis with the inflammatory bowel disease susceptibility locus IBD2 in non-Jewish Caucasians and evidence of genetic heterogeneity among racial and ethnic populations with Crohn disease.
American journal of medical genetics - 1 Dec 2002
Uthoff Sonja M S, Crawford Nigel P S, Eichenberger M Robert, Hamilton Crystal J, Petras Robert E, Martin Eden R, Galandiuk Susan
Abstract excerpt
Genomewide scanning has been used to identify chromosomal regions encoding susceptibility loci to inflammatory bowel disease (IBD). The greatest evidence for linkage to IBD has been reported for a region of chromosome 12q14 surrounding the microsatellite marker D12S83, with a logarithm of odds score of 5.47 and a positive transmission disequilibrium test, and which was subsequently named IBD2. We wished to...
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