Article
American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12.
Gastroenterology - 1 Nov 1998
Brant S R, Fu Y, Fields C T, Baltazar R, Ravenhill G, Pickles M R, Rohal P M, Mann J, Kirschner B S, Jabs E W, Bayless T M, Hanauer S B, Cho J H
Abstract excerpt
BACKGROUND & AIMS: Two European genome-wide screens for inflammatory bowel disease have identified two significant regions of linkage on chromosomes 16 (IBD1) and 12 (IBD2) and two regions with suggestive levels of significance (chromosomes 3p and 7q). The aim of this study was to determine if th...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 12
- Chromosomes, Human, Pair 16
- Crohn Disease
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Jews
- United States
- White People
