Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12.

Gastroenterology - 1 Nov 1998

Brant S R, Fu Y, Fields C T, Baltazar R, Ravenhill G, Pickles M R, Rohal P M, Mann J, Kirschner B S, Jabs E W, Bayless T M, Hanauer S B, Cho J H

Abstract excerpt

BACKGROUND & AIMS: Two European genome-wide screens for inflammatory bowel disease have identified two significant regions of linkage on chromosomes 16 (IBD1) and 12 (IBD2) and two regions with suggestive levels of significance (chromosomes 3p and 7q). The aim of this study was to determine if there was evidence for linkage to these regions in non-Jewish and Ashkenazi Jewish families multiplex for Crohn's disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 12

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 16

Share to Genetic Linkage

Share to Genetic Predisposition to Disease

Share to United States

Share to White People

Source

Identifiers

PMID: 9797357
DOI: 10.1016/s0016-5085(98)70073-3

Genes

NPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12.PMID 9797357Read ↗

Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16.Semantic proximity Read ↗

Additional evidence of linkage between Crohn's disease and a putative locus on chromosome 12.Semantic proximity Read ↗

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort.Semantic proximity Read ↗

A genome-wide search identifies potential new susceptibility loci for Crohn's disease.Semantic proximity Read ↗

Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.Semantic proximity Read ↗

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.Semantic proximity Read ↗

The IBD1 locus for susceptibility to Crohn's disease has a greater impact in Ashkenazi Jews with early onset disease.Semantic proximity Read ↗

An SNP linkage scan identifies significant Crohn's disease loci on chromosomes 13q13.3 and, in Jewish families, on 1p35.2 and 3q29.Semantic proximity Read ↗

Replication and extension studies of inflammatory bowel disease susceptibility regions confirm linkage to chromosome 6p (IBD3).Semantic proximity Read ↗

International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn disease and chromosome 16.Semantic proximity Read ↗

Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis.Semantic proximity Read ↗

A genome scan in 260 inflammatory bowel disease-affected relative pairs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.