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A population- and family-based study of Canadian families reveals association of HLA DRB1*0103 with colonic involvement in inflammatory bowel disease.

Inflammatory bowel diseases - 1 Jan 2003

Silverberg Mark S, Mirea Lucia, Bull Shelley B, Murphy Janet E, Steinhart A Hillary, Greenberg Gordon R, McLeod Robin S, Cohen Zane, Wade Judith A, Siminovitch Katherine A

Abstract excerpt

The aim of this study was to identify major histocompatibility complex alleles associated with the development and clinical features of inflammatory bowel disease (IBD). Genotyping at the human leukocyte antigen (HLA) DRB1 and DQB1 loci was performed on individuals from 118 Caucasian IBD sibling pair families and on 216 healthy controls. Both population- and family-based association tests were used to analyze...

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Identifiers

PMID: 12656131
DOI: 10.1097/00054725-200301000-00001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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