Article
Genetic analyses of chromosome 12 loci in Crohn's disease.
Gut - 1 Dec 2000
Lesage S, Zouali H, Colombel J F, Belaiche J, Cézard J P, Tysk C, Almer S, Gassull M, Binder V, Chamaillard M, Le Gall I, Thomas G, Hugot J P
Abstract excerpt
BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) includes ulcerative colitis and Crohn's disease, both of which are multifactorial diseases involving the interaction of genetic and environmental factors. A region on chromosome 12 centred around the marker locus D12S83 has previously been associated with IBD predisposition. The aim of the study was to investigate this genetic region in an independent panel of...
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