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Article

Genetic Complexity of Crohn's Disease in Two Large Ashkenazi Jewish Families.

Gastroenterology - 1 Oct 2016

Levine Adam P, Pontikos Nikolas, Schiff Elena R, Jostins Luke, Speed Doug, Lovat Laurence B, Barrett Jeffrey C, Grasberger Helmut, Plagnol Vincent, Segal Anthony W

Abstract excerpt

BACKGROUND & AIMS: Crohn's disease (CD) is a highly heritable disease that is particularly common in the Ashkenazi Jewish population. We studied 2 large Ashkenazi Jewish families with a high prevalence of CD in an attempt to identify novel genetic risk variants. METHODS: Ashkenazi Jewish patients with CD and a positive family history were recruited from the University College London Hospital. We used genome-wide,...

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Identifiers

PMID: 27373512
DOI: 10.1053/j.gastro.2016.06.040
PMCID: PMC5643259

Genes

DUOX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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