Article
Molecular characteristics and functional analysis of full-length hepatitis B virus quasispecies from a patient with chronic hepatitis B virus infection.
Virus research - 1 Jun 2010
Cui Xiu-Ji, Cho Yoo-Kyung, Song Hyun Joo, Choi Eun Kwang, Kim Heung Up, Song Byung-Cheol
Abstract excerpt
It has been hypothesized that naturally occurring mutations in HBV may play a role in the pathogenesis of HBV-related disease. We determined the molecular characteristics of naturally occurring HBV isolates and performed a functional analysis of full-length hepatitis B virus quasispecies from a patient with chronic hepatitis B. The 10 HBV clones isolated were identified as HBV genotype B4 and subtype adw. In most...
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