Article
DPEP1, expressed in the early stages of colon carcinogenesis, affects cancer cell invasiveness.
Journal of gastroenterology - 1 Feb 2011
Toiyama Yuji, Inoue Yasuhiro, Yasuda Hiromi, Saigusa Susumu, Yokoe Takeshi, Okugawa Yoshinaga, Tanaka Koji, Miki Chikao, Kusunoki Masato
Abstract excerpt
BACKGROUND: We investigated changes in the gene expression profile in colon cancer in order to identify gene markers that may be useful in the management of this disease. METHODS: The Cancer Genome Anatomy Project was used to detect differences in gene expression between normal and cancer tissue. The overexpression of dipeptidase-1 (DPEP1) in cancer tissue was confirmed in a sample of 76 patients by real-time...
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