Cytokine gene polymorphisms in inflammatory bowel disease.

doi:10.1136/gut.39.5.705

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Article

Cytokine gene polymorphisms in inflammatory bowel disease.

Gut - 1 Nov 1996

Louis E, Satsangi J, Roussomoustakaki M, Parkes M, Fanning G, Welsh K, Jewell D

Abstract excerpt

BACKGROUND: Concordance rates in siblings and twins provide strong evidence that genetic susceptibility is important in the pathogenesis of inflammatory bowel disease. The number and identity of susceptibility genes is largely uncertain. Cytokine genes are attractive candidate loci. AIMS: To stud...

Topics

Adult
Alleles
Colitis, Ulcerative
Crohn Disease
Cytokines
Disease Susceptibility
Female
Humans
Inflammatory Bowel Diseases
Male
Minisatellite Repeats
Polymerase Chain Reaction
Polymorphism, Genetic
Receptors, Interleukin-1
Tumor Necrosis Factor-alpha

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