Article
Two ubiquitin-conjugating enzymes, Rhp6 and UbcX, regulate heterochromatin silencing in Schizosaccharomyces pombe.
Molecular and cellular biology - 1 Dec 2002
Choi Eun Shik, Kim Hyun Soo, Jang Yeun Kyu, Hong Seung Hwan, Park Sang Dai
Abstract excerpt
Methylation of histone H3 has been linked to the assembly of higher-order chromatin structures. Very recently, several examples, including the Schizosaccharomyces pombe mating-type region, chicken beta-globin locus, and inactive X-chromosome, revealed that H3-Lys9-methyl (Me) is associated with silent chromatin while H3-Lys4-Me is prominent in active chromatin. Surprisingly, it was shown that homologs of...
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