Article
Hrp3, a chromodomain helicase/ATPase DNA binding protein, is required for heterochromatin silencing in fission yeast.
Biochemical and biophysical research communications - 26 Jul 2002
Jae Yoo Eung, Kyu Jang Yeun, Ae Lee Myung, Bjerling Pernilla, Bum Kim Jae, Ekwall Karl, Hyun Seong Rho, Dai Park Sang
Abstract excerpt
Hrp3, a paralog of Hrp1, is a novel member of the CHD1 (chromo-helicase/ATPase-DNA binding 1) protein family of Schizosaccharomyces pombe. Although it has been considered that CHD1 proteins are required for chromatin modifications in transcriptional regulations, little is known about their roles in vivo. In this study, we examined the effects of Hrp3 on heterochromatin silencing using several S. pombe reporter...
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