Apolipoprotein E epsilon 4 allele frequency in demented and cognitively impaired patients with and without cerebrovascular disease.

doi:10.1016/s0022-510x(02)00287-3

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Article

Apolipoprotein E epsilon 4 allele frequency in demented and cognitively impaired patients with and without cerebrovascular disease.

Journal of the neurological sciences - 15 Nov 2002

Traykov Latchezar, Rigaud Anne-Sophie, Baudic Sophie, Smagghe Alain, Boller François, Forette Françoise

Abstract excerpt

Controversy exists regarding the apolipoprotein E (ApoE) epsilon 4 allele association with vascular dementia (VaD). The results range from increased epsilon 4 frequency, similar to that found for Alzheimer's disease (AD), to no association at all. Our objective was to clarify the relationship bet...

Topics

Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoproteins E
Cognition Disorders
Dementia, Vascular
Female
Gene Frequency
Humans
Male
Phenotype
Psychiatric Status Rating Scales

Source

Open in PubMed

Identifiers

PMID: 12417380
DOI: 10.1016/s0022-510x(02)00287-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-12417380-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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