Article
Apolipoprotein E epsilon4 allele frequency in vascular dementia.
Dementia and geriatric cognitive disorders - 1 Jan 2006
Davidson Yvonne, Gibbons Linda, Purandare Nitin, Byrne Jane, Hardicre Jayne, Wren Joanne, Payton Antony, Pendleton Neil, Horan Michael, Burns Alistair, Mann David M A
Abstract excerpt
AIM: The aim of the study was to investigate whether possession of the epsilon4 allelic form of the apolipoprotein E (APOE) gene increases the risk of developing vascular dementia (VaD). METHODS: APOE allele and genotype frequencies were determined by PCR in 89 patients with possible and probable VaD and compared with those in 97 patients with possible and probable Alzheimer's disease (AD) of similar age of...
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