Article
Apolipoprotein E as vascular risk factor in neurodegenerative dementia.
International journal of molecular medicine - 1 Oct 2004
Folin Marcella, Baiguera Silvia, Conconi Maria Teresa, Di Liddo Rosa, De Carlo Eugenio, Parnigotto Pier Paolo, Nussdorfer Gastone G
Abstract excerpt
Apolipoprotein E (ApoE) is the major lipid-carrier protein in the brain, and several studies provided evidence that ApoE epsilon4 allele can be considered a genetic risk factor for vascular diseases. Findings indicate that Alzheimer disease (AD) and vascular dementia (VaD) may have common risk factors and/or pathogenesis, but their interrelationships still need to be clearly defined. Since ApoE4 imparts risk for...
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