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Article

Association between APOE epsilon4 allele and vascular dementia: The Cache County study.

Dementia and geriatric cognitive disorders - 1 Jan 2010

Chuang Yi-Fang, Hayden Kathleen M, Norton Maria C, Tschanz Joann, Breitner John C S, Welsh-Bohmer Kathleen A, Zandi Peter P

Abstract excerpt

BACKGROUND: The APOE epsilon4 allele is an established risk factor for Alzheimer's disease, but reports of its association with vascular dementia (VaD) have been inconsistent. We examined the relationship between APOE epsilon4 allele and the risk of incident VaD in a large, population-based cohort of elderly adults with up to 10 years of follow-up between 1995 and 2005. METHODS: A total of 3,424 elderly men and...

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Source

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Identifiers

PMID: 20375505
DOI: 10.1159/000285166
PMCID: PMC2865397

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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