Article
Apolipoprotein E phenotypes in demented and cognitively impaired patients with and without cerebrovascular disease.
European journal of neurology - 1 Jul 1999
Traykov L, Rigaud A S, Caputo L, Couderc R, Coste J, Michot J L, de Rotrou J, Amouyel P, Forette F, Boller F
Abstract excerpt
Controversy exists regarding the apolipoprotein E (ApoE) epsilon4 allele association with vascular dementia (VaD), ranging from increased epsilon4 frequency, similar to that found for Alzheimer's disease (AD), to no association between the epsilon4 allele and VaD. To clarify further the relations...
Topics
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Cerebrovascular Disorders
- Cognition Disorders
- Dementia
- Dementia, Vascular
- Female
- Gene Frequency
- Humans
- Male
- Phenotype
- Polymorphism, Genetic