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Article

Role of the carboxyl terminus on the catalytic activity of protein kinase CK2alpha subunit.

FEBS letters - 6 Nov 2002

Tapia Julio, Jacob Germaine, Allende Catherine C, Allende Jorge E

Abstract excerpt

Protein kinase CK2 (also known as casein kinase 2) has catalytic (alpha, alpha') and regulatory (beta) subunits. The role of carboxyl amino acids in positions from 324 to 328 was studied for Xenopus laevis CK2alpha. Deletions and mutations of these residues were produced in recombinant CK2alpha, which was assayed for kinase activity. Activity dropped 7000-fold upon deletion of amino acids 324-328. The key...

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Identifiers

PMID: 12417343
DOI: 10.1016/s0014-5793(02)03555-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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