Article
Interactions of protein kinase CK2 subunits.
Molecular and cellular biochemistry - 1 Jan 1999
Korn I, Gutkind S, Srinivasan N, Blundell T L, Allende C C, Allende J E
Abstract excerpt
Several approaches have been used to study the interactions of the subunits of protein kinase CK2. The inactive mutant of CK2alpha that has Asp 156 mutated to Ala (CK2alphaA156) is able to bind the CK2beta subunit and to compete effectively in this binding with wild-type subunits alpha and alpha'. The interaction between CK2alphaA156 and CK2beta was also demonstrated by transfection of epitope-tagged cDNA...
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