Article
Minimal CK2 activity required for yeast growth.
Molecular and cellular biochemistry - 1 Jun 2005
Hermosilla German H, Tapia Julio C, Allende Jorge E
Abstract excerpt
Protein kinase CK2 is essential for the growth of Saccharomyces cerevisiae. Yeast cells that lack the functional genes coding for both the catalytic subunits of protein kinase CK2 can grow only if they are complemented by exogenous cDNAs coding for this subunit. A series of deletion mutants of CK2alpha from Xenopus laevis was constructed. These mutants that have carboxyl end deletions yield a CK2alpha product...
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