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Article

Effect of ethylnitrosourea on HPRT gene in human promyelocytic leukemia cells.

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Mar 2002

Liu Shengxue, Cao Jia, An Hui

Abstract excerpt

OBJECTIVE: To explore the molecular spectra and mechanism of human hypoxanthine guanine phosphoribosyl transferase (HPRT) gene mutation induced by ethyluitrosourea (ENU). METHODS: Single cell cloning culture, two-way screening, multiple PCR amplification and electrophoresis technique were used. RESULTS: With dose of ENU increasing, cell plating efficiency reduced (in the group with 100-200 micro g/ml doses, P <...

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PMID: 12410959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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