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Article

[Research progress in hypoxanthine-guanine phosphoribosyltrans-ferase].

Yi chuan = Hereditas - 1 Aug 2013

Ding Hui, Yue Li-Jie, Yang Chun-Lan

Abstract excerpt

Hypoxanthine-guanine phosphoribosyltransferase (HPRT) is a cytoplasmic enzyme which is widely distributed in the body. It not only involves in the purine salvage pathway, but also relates to the metabolism of purine analogues drugs. It is a critical transferase regulating the pharmacological effects and toxicity of purine analogues drugs. The mutations of the gene for HPRT, which influence its activity, may cause...

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Identifiers

PMID: 23956083
DOI: 10.3724/sp.j.1005.2013.00948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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