Article
Effects of selective endocrine or exocrine induction of AR42J on SNARE and Munc18 protein expression.
Pancreas - 1 Nov 2002
Huang Xiaohang, Sheu Laura, Kang Youhou, Eto Yuzuru, Kojima Itaru, Gaisano Herbert Y
Abstract excerpt
INTRODUCTION AND AIM: We used the amphicrine AR42J as an excellent model to study the differentiation of the secretory machinery of pancreatic endocrine and exocrine cells. Dexamethasone treatment induced the AR42J to differentiate towards the exocrine phenotype capable of secreting amylase in response to cholecystokinin. In contrast, activin A plus hepatocyte growth factor treatment of a subclone of AR42J,...
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