Article
Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain.
Molecular biology of the cell - 1 Feb 2007
Yu Miao, Kasai Kazuo, Nagashima Kazuaki, Torii Seiji, Yokota-Hashimoto Hiromi, Okamoto Koichi, Takeuchi Toshiyuki, Gomi Hiroshi, Izumi Tetsuro
Abstract excerpt
Rab27a and Rab27b have recently been recognized to play versatile roles in regulating the exocytosis of secretory granules and lysosome-related organelles by using multiple effector proteins. However, the precise roles of these effector proteins in particular cell types largely remain uncharacterized, except for those in pancreatic beta cells and in melanocytes. Here, we showed that one of the Rab27a/b effectors,...
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