Article
Rab3D regulates amylase levels, not agonist-induced amylase release, in AR42J cells.
Cellular & molecular biology letters - 1 Jun 2012
Limi Saima, Ojakian George, Raffaniello Robert
Abstract excerpt
Rab3D is a low molecular weight GTP-binding protein that associates with secretory granules in exocrine cells. AR42J cells are derived from rat pancreatic exocrine tumor cells and develop an acinar cell-like phenotype when treated with dexamethasone (Dex). In the present study, we examined the role of Rab3D in Dex-treated AR42J cells. Rab3D expression and localization were analyzed by subcellular fractionation...
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