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Article

Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: consideration of pancreas differentiation.

Differentiation; research in biological diversity - 1 Jan 2000

Itoh Masayuki, Takizawa Yuji, Hanai Sae, Okazaki Shin, Miyata Rie, Inoue Takeshi, Akashi Takumi, Hayashi Masaharu, Goto Yu-ichi

Abstract excerpt

Aristaless-related homeobox gene (ARX) mutation leads to several neurological disorders including X-linked lissencephaly with abnormal genitalia (XLAG), West syndrome and Partington syndrome, with XLAG being the most severe form. Although some of the brain pathologies of XLAG have already been described, the crucial extra-brain symptoms are severe growth retardation, transient hyperglycemia and intractable...

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Source

Identifiers

PMID: 20538404
DOI: 10.1016/j.diff.2010.05.003

Genes

ARX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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