Article
Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation.
Development (Cambridge, England) - 1 Dec 2002
Dubruille Raphaelle, Laurençon Anne, Vandaele Camille, Shishido Emiko, Coulon-Bublex Madeleine, Swoboda Peter, Couble Pierre, Kernan Maurice, Durand Bénédicte
Abstract excerpt
Ciliated neurons play an important role in sensory perception in many animals. Modified cilia at dendrite endings serve as sites of sensory signal capture and transduction. We describe Drosophila mutations that affect the transcription factor RFX and genetic rescue experiments that demonstrate its central role in sensory cilium differentiation. Rfx mutant flies show defects in chemosensory and mechanosensory...
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