Article
The in vivo dissection of direct RFX-target gene promoters in C. elegans reveals a novel cis-regulatory element, the C-box.
Developmental biology - 15 Aug 2012
Burghoorn Jan, Piasecki Brian P, Crona Filip, Phirke Prasad, Jeppsson Kristian E, Swoboda Peter
Abstract excerpt
At the core of the primary transcriptional network regulating ciliary gene expression in Caenorhabditis elegans sensory neurons is the RFX/DAF-19 transcription factor, which binds and thereby positively regulates 13-15 bp X-box promoter motifs found in the cis-regulatory regions of many ciliary genes. However, the variable expression of direct RFX-target genes in various sets of ciliated sensory neurons (CSNs)...
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