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Identification of novel regulatory factor X (RFX) target genes by comparative genomics in Drosophila species

17 Sept 2007

Abstract excerpt

BACKGROUND: Regulatory factor X (RFX) transcription factors play a key role in ciliary assembly in nematode, Drosophila and mouse. Using the tremendous advantages of comparative genomics in closely related species, we identified novel genes regulated by dRFX in Drosophila. RESULTS: We first demonstrate that a subset of known ciliary genes in Caenorhabditis elegans and Drosophila are regulated by dRFX and have a...

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PMID: 17875208
DOI: 10.1186/gb-2007-8-9-r195

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