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Identification of ciliary and ciliopathy genes in Caenorhabditis elegansthrough comparative genomics

22 Dec 2006

Abstract excerpt

BACKGROUND: The recent availability of genome sequences of multiple related Caenorhabditis species has made it possible to identify, using comparative genomics, similarly transcribed genes in Caenorhabditis elegans and its sister species. Taking this approach, we have identified numerous novel ciliary genes in C. elegans, some of which may be orthologs of unidentified human ciliopathy genes. RESULTS: By screening...

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PMID: 17187676
DOI: 10.1186/gb-2006-7-12-r126

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