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Article

Identification of a single nucleotide polymorphism in the choline acetyltransferase gene associated with Alzheimer's disease.

Neuroscience letters - 15 Nov 2002

Mubumbila Victor, Sutter Anne, Ptok Ursula, Heun Reinhard, Quirin-Stricker Christiane

Abstract excerpt

The dysfunction of the cholinergic system in Alzheimer's disease (AD) supports the hypothesis that a decline in choline acetyltransferase (ChAT) activity in memory as well as in cognitive functions in AD might be functionally linked. To assess the physiological relevance of an allelic variation in the ChAT gene we investigated the presence of a possible polymorphism in AD patients and in elderly non-demented...

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Identifiers

PMID: 12401548
DOI: 10.1016/s0304-3940(02)00955-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a single nucleotide polymorphism in the choline acetyltransferase gene associated with Alzheimer's disease.PMID 12401548Read ↗

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