Genetic variants in the choline acetyltransferase (ChAT) gene are modestly associated with normal cognitive function in the elderly.

doi:10.1111/j.1601-183X.2011.00728.x

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Article

Genetic variants in the choline acetyltransferase (ChAT) gene are modestly associated with normal cognitive function in the elderly.

Genes, brain, and behavior - 1 Nov 2011

Mengel-From J, Christensen K, Thinggaard M, McGue M, Christiansen L

Abstract excerpt

Genetic variants in the choline acetyltransferase (ChAT) gene have been suggested as risk factors for neurodegenerative Alzheimer's disease (AD). Here we tested the importance of genetic variants in the ChAT gene in normal cognitive function of elderly in a study sample of Danish twins and singletons (N = 2070). The ChAT rs3810950 A allele, which has been associated with increased risk for AD, was found to be...

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PMID: 21883924
DOI: 10.1111/j.1601-183X.2011.00728.x
PMCID: PMC3212625

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APOE

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Genetic variants in the choline acetyltransferase (ChAT) gene are modestly associated with normal cognitive function in the elderly.PMID 21883924Read ↗

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CHAT gene polymorphism rs3810950 is associated with the risk of Alzheimer's disease in the Czech population.Semantic proximity Read ↗

Association of Choline Acetyltransferase Gene Polymorphisms (SNPs rs868750G/A, rs1880676G/A, rs2177369G/A and rs3810950G/A) with Alzheimer's Disease Risk: A Meta-Analysis.Semantic proximity Read ↗

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Choline acetyltransferase 2384G>a polymorphism and the risk of Alzheimer disease.Semantic proximity Read ↗

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Association of CHAT Gene Polymorphism rs3793790 and rs2177370 with Donepezil Response and the Risk of Alzheimer's Disease Continuum.Semantic proximity Read ↗

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