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Article

Genetic variation in the choline acetyltransferase (CHAT) gene may be associated with the risk of Alzheimer's disease.

Neurobiology of aging - 1 Oct 2006

Ozturk Ayla, DeKosky Steven T, Kamboh M Ilyas

Abstract excerpt

Several independent linkage studies have mapped a broad susceptibility region for Alzheimer's disease (AD) on the long arm of chromosome 10. There are several biological candidate genes in this region, including choline acetyltransferase (CHAT). A number of studies have examined the role of CHAT genetic variants with AD risk and age-at-onset (AAO), but the results are equivocal. We examined the association of...

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Identifiers

PMID: 16223550
DOI: 10.1016/j.neurobiolaging.2005.08.024
PMCID: PMC1609962

Genes

CHAT
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in the choline acetyltransferase (CHAT) gene may be associated with the risk of Alzheimer's disease.PMID 16223550Read ↗

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