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Article

Timing requirements for insulin/IGF-1 signaling in C. elegans.

Science (New York, N.Y.) - 25 Oct 2002

Dillin Andrew, Crawford Douglas K, Kenyon Cynthia

Abstract excerpt

The insulin/IGF-1 (where IGF-1 is insulin-like growth factor-1) signaling pathway influences longevity, reproduction, and diapause in many organisms. Because of the fundamental importance of this system in animal physiology, we asked when during the animal's life it is required to regulate these...

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Identifiers

PMID: 12399591
DOI: 10.1126/science.1074240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12399591-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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