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Article

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans.

Science (New York, N.Y.) - 15 Aug 1997

Kimura K D, Tissenbaum H A, Liu Y, Ruvkun G

Abstract excerpt

A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decrea...

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PMID: 9252323
DOI: 10.1126/science.277.5328.942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9252323-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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