Article
Control of oxidative stress resistance by IP3 kinase in Drosophila melanogaster.
Free radical biology & medicine - 1 Nov 2002
Monnier Véronique, Girardot Fabrice, Audin Wilfried, Tricoire Hervé
Abstract excerpt
Oxidative damage is thought to be a major causal factor of aging, and is implicated in several human pathologies such as Alzheimer's and Parkinson's diseases. Nevertheless the genetical determinants of in vivo oxidative stress response are still poorly understood. To identify cellular components whose deregulation leads to oxidative stress resistance, we performed a genetic screen in Drosophila melanogaster. We...
Topics
- Animals
- Animals, Genetically Modified
- Blotting, Northern
- Calcium
- Catalase
- Drosophila melanogaster
- Drug Resistance
- Female
- Genotype
- Herbicides
- Hydrogen Peroxide
