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Article

Innate immune responses to paraquat exposure in a Drosophila model of Parkinson’s disease

3 Sept 2019

Abstract excerpt

Parkinson's disease (PD) is a progressive, neurodegenerative movement disorder characterized by the loss of dopaminergic (DA) neurons. Limited understanding of the early molecular pathways associated with the demise of DA neurons, including those of inflammatory exacerbation of neurodegeneration, is a major impediment to therapeutic development. Recent studies have implicated gene-environment interactions in PD...

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PMID: 31481676
DOI: 10.1038/s41598-019-48977-6

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