Article
Mutation in Drosophila methuselah resists paraquat induced Parkinson-like phenotypes.
Neurobiology of aging - 1 Oct 2014
Shukla Arvind K, Pragya Prakash, Chaouhan Hitesh S, Patel D K, Abdin M Z, Kar Chowdhuri Debapratim
Abstract excerpt
Parkinson's disease (PD) is a prevalent and devastating neurodegenerative disorder having limited cure options and strong association with the loss of dopaminergic neurons in the substantia nigra region of the mid brain. Etiology of PD includes both genetic and environmental factors. Paraquat (PQ), a widely used herbicide, is known to be associated with pathogenesis of PD. We report that a mutation in Drosophila...
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