Article
Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.
Blood - 15 Dec 2002
Fröhling Stefan, Schlenk Richard F, Breitruck Jochen, Benner Axel, Kreitmeier Sylvia, Tobis Karen, Döhner Hartmut, Döhner Konstanze
Abstract excerpt
To assess the prognostic relevance of activating mutations of the FLT3 gene in homogeneously treated adults 16 to 60 years of age with acute myeloid leukemia (AML) and normal cytogenetics, pretreatment samples from 224 patients entered into 2 consecutive multicenter treatment trials were analyzed for FLT3 internal tandem duplications (ITDs) and Asp835 mutations. Treatment included intensive double-induction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.