Article
Mutation of FLT3 gene in acute myeloid leukemia with normal cytogenetics and its association with clinical and immunophenotypic features.
Medical oncology (Northwood, London, England) - 1 Jun 2011
Chauhan Pradeep S, Bhushan Bharat, Mishra Ashwani K, Singh Laishram C, Saluja Sumita, Verma Saurabh, Gupta Dipendra K, Mittal Vishakha, Chaudhry Sumita, Kapur Sujala
Abstract excerpt
Acute myeloid leukemia (AML) with normal karyotype represents a clinically and molecularly heterogeneous disease. Molecular markers with prognostic significance have been examined to improve risk profile characterization of this group. Activating mutations on FLT3 receptor are one of the most common genetic alterations reported. However, the prevalence and prognostic significance of FLT3 genetic alterations in...
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