Article
Expression of folate sensitive and aphidicolin induced chromosomal fragile sites in familial neuroblastoma.
Journal of experimental & clinical cancer research : CR - 1 Sept 2002
Ankathil R, Kusumakumary P, Priyakumary T, Krishnan Nair M
Abstract excerpt
The expression of folate sensitive and aphidicolin induced fragile sites in the blood lymphocyte chromosomes of affected and unaffected members from 2 neuroblastoma families were studied. The subjects included 4 neuroblastoma patients, and 9 of their clinically healthy first degree relatives and corresponding number of age and sex matched controls. Lymphocytes cultured in folate deprived culture medium showed...
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