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Article

The expression of fragile sites in lymphocytes of patients with rectum cancer and their first-degree relatives.

Cancer letters - 1 May 2000

Tunca B, Egeli U, Zorluoğlu A, Yilmazlar T, Yerci O, Kizil A

Abstract excerpt

Fragile sites are non-staining gaps and breaks in specific points of chromosomes. These sites also include acentric fragments, triradial figures and several rearrangements. Although this issue has been controversial recently, they may be related to structural chromosomal rearrangement in some neoplasms. In this study, the expression of fragile sites induced by aphidicolin (Apc), 5-bromodeoxyuridine (BrdU) and...

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Identifiers

PMID: 10773413
DOI: 10.1016/s0304-3835(00)00334-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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