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Article

[Detection of P53 and K-ras gene mutations in lung cancer with oligonucleotide chip].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Jul 2002

Liu Jun-Bo, Xie Ji-Pan, Zou Zong-Liang, Chen Lin-Jie, Li Long-Yun, Wang Sheng-Qi

Abstract excerpt

Different factors including hybridization solution components, hybridization temperature, and the concentration and proportion of the labelled primer, which affected the sensitivity and specificity of single mutation identification, were exploited. Asymmetric PCR increased the hybridization sensitivity, and the asymmetric multi-PCR did not affect the specificity, while the sensitivity was improved a little. Among...

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PMID: 12385241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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