Article
[p53 gene mutations in the human lung carcinoma].
Nihon rinsho. Japanese journal of clinical medicine - 1 Feb 1996
Saito M, Takahashi S, Uesaka Y, Enomoto K
Abstract excerpt
The p53 mutations in the reported 243 lung cancers and our 59 cases were analyzed. The common base substitutions found in the lung cancer were G to T transversion (35%), C:G to T:A (26%) and A:T to G:C transitions (11%). Four types of the hot spot, 1) G to T transversion, 2) A to G transition in ApT site, 3) C to T transition in CpG site and 4) mix of the transversion and transition were identified. It is...
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