Article
Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jun 1999
Ahrendt S A, Halachmi S, Chow J T, Wu L, Halachmi N, Yang S C, Wehage S, Jen J, Sidransky D
Abstract excerpt
The p53 gene was sequenced in 100 primary human lung cancers by using direct dideoxynucleotide cycle sequencing and compared with sequence analysis by using the p53 GeneChip assay. Differences in sequence analysis between the two techniques were further evaluated to determine the accuracy and limitations of each method. p53 mutations were either detected by using both techniques or, if only detected by one...
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