Article
[Application of oligonucleotide microarray primer extension to detection of p53 single nucleotide polymorphisms].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Jul 2005
Wu Qing-Hua, Ma Wen-Li, Zhang Bao, Guo Qiu-Ye, Li Ling, Zheng Wen-Ling
Abstract excerpt
BACKGROUND & OBJECTIVE: Increasing evidences imply that single nucleotide polymorphisms (SNPs) are involved in etiopathology, individual therapy, and prognosis of many diseases. Rapid and accurate SNPs detection in disease genes is vitally important for genomic research. To detect p53 SNPs, the method of an arrayed primer extension based on oligonucleotide microarray was developed. METHODS: Twelve extension...
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